|
09/02/2010 01:00 AM
|
|
New Light On The Mechanism Of Parkinson's Disease
|
A significant number of Parkinson's disease patients have a mutation of the enzyme Leucine-Rich Repeat Protein Kinase 2 (LRRK2, also known as dardarin). However, little is understood about how it is regulated or functions...
|
|
08/28/2010 12:00 AM
|
|
New Parkinson's Gene Is Linked To Immune System
|
A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development...
|
|
08/27/2010 01:00 AM
|
|
Impax Pharmaceuticals Completes Enrollment In ADVANCE-PD Phase III Trial Of IPX066 In Parkinson's Disease
|
Impax Pharmaceuticals, the brand products division of Impax Laboratories, Inc. (NASDAQ: IPXL), announced that it has completed enrollment of its ADVANCE-PD trial. ADVANCE-PD is a multinational Phase III trial of its late-stage product IPX066 in advanced Parkinson's disease (PD) patients with motor fluctuations...
|
|
08/25/2010 02:00 AM
|
|
Lipid Peroxides, More Sophisticated Than Their Reputation
|
Accumulation of lipid peroxides in the cell are associated with diseases and cellular stress. In the current issue of PNAS researchers at Helmholtz Zentrum München and the Swedish medical university Karolinska Institutet show that lipid peroxides also play an important, yet-unrecognized role in the regulation of receptor tyrosine kinases...
|
|
08/25/2010 01:00 AM
|
|
Alnylam And Collaborators Publish New Pre-Clinical Research On Therapeutic Silencing Of Parkinson's Disease Gene
|
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and collaborators at The Parkinson's Institute and the Mayo Clinic have published new research findings in the journal Public Library of Science (PLoS)...
|
|
08/24/2010 03:00 AM
|
|
A Promising Target For Developing Treatments Against Parkinson's Disease
|
Researchers at Johns Hopkins have shown that using specific drugs can protect nerve cells in mice from the lethal effects of Parkinson's disease. The researchers' findings are published in the August 22 issue of Nature Medicine. The newly discovered drugs block a protein that, when altered in people, leads to Parkinson's disease...
|
|
08/24/2010 01:00 AM
|
|
A Promising Target For Developing Treatments Against Parkinson's Disease
|
Researchers at Johns Hopkins have shown that using specific drugs can protect nerve cells in mice from the lethal effects of Parkinson's disease. The researchers' findings are published in the August 22 issue of Nature Medicine. The newly discovered drugs block a protein that, when altered in people, leads to Parkinson's disease...
|
|
08/20/2010 12:00 AM
|
|
Brain Connections Break Down As We Age
|
It's unavoidable: breakdowns in brain connections slow down our physical response times as we age, a new study suggests...
|
|
08/18/2010 12:00 AM
|
|
Human Induced Pluripotent Stem Cells Successfully Used To Treat Parkinson's In Rodents
|
Researchers at the Buck Institute for Age Research have successfully used human induced pluripotent stem cells (iPSCs) to treat rodents afflicted with Parkinson's Disease (PD)...
|
|
08/16/2010 02:00 AM
|
|
Genetic Link Discovered Between Immune System, Parkinson's Disease
|
A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics...
|
|
08/16/2010 02:00 AM
|
|
Immune System Genes Linked To Parkinson's Disease
|
An international team of researchers conducting a genome-wide association study (GWAS) has discovered that common variants in immune system genes are linked to Parkinson's disease...
|
|
08/12/2010 12:00 AM
|
|
Development Of Neurochip Technology Will Further Brain Research Of Alzheimer's, Parkinson's
|
The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip - or the brain on a microchip - have been involved in the development of new technology that monitors brain cell activity at a resolution never achieved before...
|
|
08/09/2010 02:00 AM
|
|
TEMPO Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson's Disease Patients
|
H. Lundbeck A/S (Lundbeck) and Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension...
|
|
08/08/2010 12:00 AM
|
|
Expectations May Affect Placebo Response In Patients With Parkinson's Disease
|
Individuals with Parkinson's disease were more likely to have a neurochemical response to a placebo medication if they were told they had higher odds of receiving an active drug, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals...
|
|
08/06/2010 08:00 AM
|
|
TEMPO Extentension Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson's Disease Patients
|
Teva Pharmaceutical Industries Ltd. and H. Lundbeck A/S have announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension. The findings confirm the long-term efficacy, safety and tolerability of Azilect® in patients with Parkinson's disease (PD) and further demonstrate the benefits obtained with early treatment initiation...
|
|
07/30/2010 01:00 AM
|
|
New Pathway To Parkinson's And Alzheimer's Diseases
|
Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells...
|
|
07/30/2010 12:00 AM
|
|
Study Identifies Molecular Mechanism Triggering Parkinson's Disease
|
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady...
|
|
07/29/2010 09:00 AM
|
|
REM Sleep Disorder Could Be Early Warning Of Parkinson's, Dementia That Develops Decades Later
|
American neurologists and sleep experts suggest in a recent study that rapid eye movement (REM) sleep behavior disorder could be an early sign of Parkinson's disease or dementia that develops up to 50 years later. You can read how neurologist and sleep specialist Dr Bradley F...
|
|
07/29/2010 12:00 AM
|
|
Envoy To Seek New Parkinson's Disease Therapy With Scripps
|
Envoy Therapeutics Inc., a recently formed drug discovery company, announced that it has begun a research collaboration with The Scripps Research Institute to identify new drugs for Parkinson's disease (PD) that have greater efficacy and safety compared to current therapies...
|
|
07/26/2010 12:00 AM
|
|
Helping Neurons Fix Themselves In Parkinson's Patients
|
A Michigan State University researcher is working to uncover how a protein known as parkin may help nerve cells fight off damage from Parkinson's disease, a strategy that could lead to new therapies for the degenerative ailment...
|
|
07/23/2010 05:00 AM
|
|
New Partnership With Open-Access Journal Molecular Neurodegeneration Announced By American Health Assistance Foundation
|
The American Health Assistance Foundation (AHAF)has announced a new partnership with BioMed Central's open access journal, Molecular Neurodegeneration (MN) in which the publication will be the official open access journal of AHAF...
|
|
07/22/2010 02:00 AM
|
|
Every Action Has A Beginning And An End (And It's All In Your Brain)
|
Rui Costa, Principal Investigator of the Champalimaud Neuroscience Programme at the Instituto Gulbenkian de Ciência (Portugal), and Xin Jin, of the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health (USA), describe in the latest issue of the journal Nature, that the activity of certain neurons in the brain can signal the initiation and terminatio...
|
|
07/20/2010 01:00 AM
|
|
New Findings On Troubling Side Effects Of Parkinson's Medication
|
One in every 100 elderly people suffers from Parkinson's disease, a disease of the nervous system with symptoms including stiffness and shaking. The standard medication used to treat Parkinson's is Levodopa, a drug that initially has major benefits but can later also produce serious side effects in the form of involuntary, jerky movements...
|
|
07/15/2010 12:00 AM
|
|
The Cause Of Parkinson's Disease May Be Revealed With The Help Of Skin Cells
|
Researchers are applying new stem cell technology to use skin samples to grow the brain cells thought to be responsible for the onset of Parkinson's disease, the UK National Stem Cell Network (UKNSCN) annual science meeting heard...
|
|
07/13/2010 05:00 AM
|
|
Possible Link Between Low Vitamin D Levels And Parkinson's Disease
|
A new study on vitamin D levels and Parkinson's disease risk points to the need for further research on whether vitamin D supplements can protect against the movement disorder, according to an editorial in the July 2010 issue of Archives of Neurology...
|
